ETF constituents for XBI

Below, a list of constituents for XBI (SPDR® S&P® Biotech ETF) is shown. In total, XBI consists of 190 securities.

Note: The data shown here is as of date As of 11-Nov-2021 (the latest that can be sourced directly from the fund provider).

Click here to go back to the full list of ETFs.

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Name Ticker Identifier Weight Sector Shares Held
Chemocentryx Inc. CCXI 16383L10 1.90263 Biotechnology 3794809.0
Cytokinetics Incorporated CYTK 23282W60 1.017005 Biotechnology 1982219.0
Acceleron Pharma Inc XLRN 00434H10 0.994293 Biotechnology 441826.0
ACADIA Pharmaceuticals Inc. ACAD 00422510 0.976648 Biotechnology 3636829.0
Avid Bioservices Inc. CDMO 05368M10 0.948535 Biotechnology 2185659.0
Ocugen Inc OCGN 67577C10 0.92353 Biotechnology 8184021.0
Seres Therapeutics Inc MCRB 81750R10 0.918626 Biotechnology 9332648.0
Anavex Life Sciences Corp. AVXL 03279730 0.913476 Biotechnology 3129221.0
Ligand Pharmaceuticals Incorporated LGND 53220K50 0.900433 Biotechnology 427658.0
Arrowhead Pharmaceuticals Inc. ARWR 04280A10 0.899839 Biotechnology 914420.0
Karuna Therapeutics Inc. KRTX 48576A10 0.893322 Biotechnology 491483.0
Blueprint Medicines Corp. BPMC 09627Y10 0.893088 Biotechnology 592938.0
Insmed Incorporated INSM 45766930 0.890286 Biotechnology 2155268.0
Seagen Inc. SGEN 81181C10 0.889635 Biotechnology 386227.0
Kodiak Sciences Inc. KOD 50015M10 0.883936 Biotechnology 607118.0
Global Blood Therapeutics Inc GBT 37890U10 0.863401 Biotechnology 2081676.0
Apellis Pharmaceuticals Inc. APLS 03753U10 0.847739 Biotechnology 1675203.0
TG Therapeutics Inc. TGTX 88322Q10 0.846063 Biotechnology 1964232.0
OPKO Health Inc. OPK 68375N10 0.839136 Biotechnology 15799541.0
AbbVie Inc. ABBV 00287Y10 0.830767 Biotechnology 548535.0
FibroGen Inc. FGEN 31572Q80 0.818826 Biotechnology 5160076.0
Sarepta Therapeutics Inc. SRPT 80360710 0.813083 Biotechnology 727222.0
Amicus Therapeutics Inc. FOLD 03152W10 0.812015 Biotechnology 5353732.0
Relay Therapeutics Inc. RLAY 75943R10 0.808986 Biotechnology 1745052.0
BioMarin Pharmaceutical Inc. BMRN 09061G10 0.79357 Biotechnology 750383.0
Iovance Biotherapeutics Inc IOVA 46226010 0.784229 Biotechnology 2569866.0
Springworks Therapeutics Inc. SWTX 85205L10 0.782997 Biotechnology 855883.0
G1 Therapeutics Inc. GTHX 3621LQ10 0.780333 Biotechnology 3940447.0
Revolution Medicines Inc. RVMD 76155X10 0.77573 Biotechnology 1864463.0
Dicerna Pharmaceuticals Inc. DRNA 25303110 0.775267 Biotechnology 2696553.0
Ironwood Pharmaceuticals Inc. Class A IRWD 46333X10 0.765465 Biotechnology 4796331.0
Cerevel Therapeutics Holdings Inc CERE 15678U12 0.764985 Biotechnology 1538117.0
Horizon Therapeutics Public Limited Company HZNP G4618810 0.762826 Biotechnology 543168.0
Arena Pharmaceuticals Inc. ARNA 04004760 0.758441 Biotechnology 985256.0
Karyopharm Therapeutics Inc. KPTI 48576U10 0.757228 Biotechnology 6966856.0
Alector Inc. ALEC 01444210 0.755848 Biotechnology 2570950.0
Amgen Inc. AMGN 03116210 0.75218 Biotechnology 273794.0
Arcus Biosciences Inc. RCUS 03969F10 0.751827 Biotechnology 1546384.0
Denali Therapeutics Inc. DNLI 24823R10 0.751788 Biotechnology 1133391.0
Rocket Pharmaceuticals Inc. RCKT 77313F10 0.751039 Biotechnology 1656241.0
Vertex Pharmaceuticals Incorporated VRTX 92532F10 0.748909 Biotechnology 310281.0
Heron Therapeutics Inc HRTX 42774610 0.740295 Biotechnology 5022785.0
Veracyte Inc VCYT 92337F10 0.733934 Biotechnology 1202527.0
Regeneron Pharmaceuticals Inc. REGN 75886F10 0.731726 Biotechnology 89922.0
Twist Bioscience Corp. TWST 90184D10 0.727791 Biotechnology 481906.0
United Therapeutics Corporation UTHR 91307C10 0.726116 Biotechnology 278331.0
BridgeBio Pharma Inc. BBIO 10806X10 0.72259 Biotechnology 1162180.0
Gilead Sciences Inc. GILD 37555810 0.721781 Biotechnology 824305.0
Zentalis Pharmaceuticals Inc. ZNTL 98943L10 0.721529 Biotechnology 705926.0
PTC Therapeutics Inc. PTCT 69366J20 0.720564 Biotechnology 1397359.0
Myriad Genetics Inc. MYGN 62855J10 0.720537 Biotechnology 1760936.0
Kymera Therapeutics Inc. KYMR 50157510 0.720466 Biotechnology 877873.0
Agios Pharmaceuticals Inc. AGIO 00847X10 0.719825 Biotechnology 1295145.0
IVERIC bio Inc. ISEE 46583P10 0.719 Biotechnology 3209780.0
Natera Inc. NTRA 63230710 0.716022 Biotechnology 487054.0
SAGE Therapeutics Inc. SAGE 78667J10 0.713295 Biotechnology 1294894.0
Halozyme Therapeutics Inc. HALO 40637H10 0.710677 Biotechnology 1418921.0
Dynavax Technologies Corporation DVAX 26815820 0.710503 Biotechnology 3334209.0
Ionis Pharmaceuticals Inc. IONS 46222210 0.706611 Biotechnology 1621414.0
Madrigal Pharmaceuticals Inc. MDGL 55886810 0.704843 Biotechnology 590626.0
Neurocrine Biosciences Inc. NBIX 64125C10 0.700845 Biotechnology 604848.0
Travere Therapeutics Inc. TVTX 89422G10 0.698925 Biotechnology 1792300.0
Incyte Corporation INCY 45337C10 0.695626 Biotechnology 822742.0
Clovis Oncology Inc. CLVS 18946410 0.695385 Biotechnology 13421094.0
Alnylam Pharmaceuticals Inc ALNY 02043Q10 0.693713 Biotechnology 308705.0
Inovio Pharmaceuticals Inc. INO 45773H20 0.690096 Biotechnology 7360513.0
Humanigen Inc HGEN 44486320 0.689184 Biotechnology 8505228.0
Biohaven Pharmaceutical Holding Company Ltd. BHVN G1119610 0.686223 Biotechnology 434935.0
Exelixis Inc. EXEL 30161Q10 0.679158 Biotechnology 2931647.0
Intercept Pharmaceuticals Inc. ICPT 45845P10 0.6774 Biotechnology 2771794.0
Biogen Inc. BIIB 09062X10 0.67553 Biotechnology 195150.0
Exact Sciences Corporation EXAS 30063P10 0.659918 Biotechnology 564529.0
Mirati Therapeutics Inc. MRTX 60468T10 0.659379 Biotechnology 353308.0
Beam Therapeutics Inc. BEAM 07373V10 0.651317 Biotechnology 537123.0
REGENXBIO Inc. RGNX 75901B10 0.648204 Biotechnology 1329344.0
Fate Therapeutics Inc. FATE 31189P10 0.627297 Biotechnology 855140.0
Vericel Corporation VCEL 92346J10 0.626672 Biotechnology 1133365.0
CEL-SCI Corporation CVM 15083760 0.618966 Biotechnology 3998765.0
Celldex Therapeutics Inc. CLDX 15117B20 0.618813 Biotechnology 1073277.0
C4 Therapeutics Inc. CCCC 12529R10 0.618021 Biotechnology 1108866.0
BioCryst Pharmaceuticals Inc. BCRX 09058V10 0.617895 Biotechnology 3849744.0
Intellia Therapeutics Inc. NTLA 45826J10 0.617147 Biotechnology 364178.0
Ultragenyx Pharmaceutical Inc. RARE 90400D10 0.611728 Biotechnology 575469.0
Protagonist Therapeutics Inc. PTGX 74366E10 0.611019 Biotechnology 1298023.0
Alkermes Plc ALKS G0176710 0.610469 Biotechnology 1917248.0
Sorrento Therapeutics Inc. SRNE 83587F20 0.610194 Biotechnology 7388326.0
MannKind Corporation MNKD 56400P70 0.607294 Biotechnology 9428726.0
STATE STREET INSTITUTIONAL LIQ STATE STR 964WKM90 964WKM90 0.606407 Unassigned 46698170.0
Allakos Inc. ALLK 01671P10 0.60064 Biotechnology 555671.0
Myovant Sciences Ltd. MYOV G637AM10 0.591457 Biotechnology 2136344.0
Allogene Therapeutics Inc. ALLO 01977010 0.590628 Biotechnology 2365214.0
Enanta Pharmaceuticals Inc. ENTA 29251M10 0.566759 Biotechnology 479720.0
2seventy Bio Inc. TSVT 90138410 0.566635 Biotechnology 1090884.0
Vaxart Inc. VXRT 92243A20 0.566432 Biotechnology 6679902.0
Prothena Corp. Plc PRTA G7280010 0.562214 Biotechnology 766147.0
Coherus BioSciences Inc. CHRS 19249H10 0.535763 Biotechnology 2228958.0
Arcturus Therapeutics Holdings Inc. ARCT 03969T10 0.534032 Biotechnology 1098709.0
Novavax Inc. NVAX 67000240 0.53135 Biotechnology 241576.0
Invitae Corp. NVTA 46185L10 0.527793 Biotechnology 1877333.0
Curis Inc. CRIS 23126920 0.52633 Biotechnology 6710521.0
Atara Biotherapeutics Inc ATRA 04651310 0.524919 Biotechnology 2304615.0
DermTech Inc. DMTK 24984K10 0.516828 Biotechnology 1656257.0
CareDx Inc. CDNA 14167L10 0.515844 Biotechnology 842326.0
Replimune Group Inc. REPL 76029N10 0.512682 Biotechnology 1171184.0
MacroGenics Inc. MGNX 55609910 0.508109 Biotechnology 1951544.0
Agenus Inc. AGEN 00847G70 0.498003 Biotechnology 9002391.0
bluebird bio Inc. BLUE 09609G10 0.496373 Biotechnology 3272658.0
uniQure N.V. QURE N9006410 0.488797 Biotechnology 1147600.0
Sangamo Therapeutics Inc. SGMO 80067710 0.487677 Biotechnology 3740537.0
Vir Biotechnology Inc. VIR 92764N10 0.485883 Biotechnology 1131786.0
Akebia Therapeutics Inc. AKBA 00972D10 0.484815 Biotechnology 12655792.0
BioXcel Therapeutics Inc. BTAI 09075P10 0.481896 Biotechnology 1122839.0
Kura Oncology Inc. KURA 50127T10 0.481056 Biotechnology 2115656.0
Nurix Therapeutics Inc. NRIX 67080M10 0.474576 Biotechnology 1105449.0
Emergent BioSolutions Inc. EBS 29089Q10 0.471711 Biotechnology 1024986.0
PMV Pharmaceuticals Inc. PMVP 69353Y10 0.459008 Biotechnology 1492075.0
Altimmune Inc. ALT 02155H20 0.44334 Biotechnology 3081288.0
Morphic Holding Inc. MORF 61775R10 0.442845 Biotechnology 548185.0
Editas Medicine Inc. EDIT 28106W10 0.439149 Biotechnology 885287.0
Xencor Inc. XNCR 98401F10 0.437344 Biotechnology 851124.0
ImmunityBio Inc IBRX 45256X10 0.435686 Biotechnology 4290442.0
IGM Biosciences Inc. IGMS 44958510 0.425025 Biotechnology 543873.0
Turning Point Therapeutics Inc. TPTX 90041T10 0.420704 Biotechnology 743745.0
ImmunoGen Inc. IMGN 45253H10 0.417133 Biotechnology 5695490.0
Organogenesis Holdings Inc. Class A ORGO 68621F10 0.401563 Biotechnology 2801043.0
Immunovant Inc IMVT 45258J10 0.391033 Biotechnology 3555209.0
Sana Biotechnology Inc. SANA 79956610 0.3844 Biotechnology 1359754.0
Moderna Inc. MRNA 60770K10 0.381887 Biotechnology 130229.0
Mersana Therapeutics Inc. MRSN 59045L10 0.371016 Biotechnology 3042725.0
Radius Health Inc. RDUS 75046920 0.362288 Biotechnology 1483992.0
Vanda Pharmaceuticals Inc. VNDA 92165910 0.361331 Biotechnology 1533076.0
Keros Therapeutics Inc. KROS 49232710 0.352237 Biotechnology 457267.0
VBI Vaccines Inc. VBIV 91822J10 0.345238 Biotechnology 8832569.0
Spectrum Pharmaceuticals Inc. SPPI 84763A10 0.345121 Biotechnology 12964421.0
Catalyst Pharmaceuticals Inc. CPRX 14888U10 0.344146 Biotechnology 3620488.0
ALX Oncology Holdings Inc. ALXO 00166B10 0.326927 Biotechnology 575450.0
Syndax Pharmaceuticals Inc SNDX 87164F10 0.316974 Biotechnology 1384546.0
Aldeyra Therapeutics Inc. ALDX 01438T10 0.316433 Biotechnology 2719627.0
Scholar Rock Holding Corp. SRRK 80706P10 0.313808 Biotechnology 698835.0
Verastem Inc. VSTM 92337C10 0.309241 Biotechnology 8127655.0
Rubius Therapeutics Inc. RUBY 78116T10 0.302775 Biotechnology 1616928.0
Recursion Pharmaceuticals Inc Class A RXRX 75629V10 0.295415 Biotechnology 1277333.0
Generation Bio Co. GBIO 37148K10 0.293941 Biotechnology 1069238.0
Albireo Pharma Inc. ALBO 01345P10 0.287509 Biotechnology 785122.0
Krystal Biotech Inc. KRYS 50114710 0.280003 Biotechnology 436664.0
Kiniksa Pharmaceuticals Ltd. Class A KNSA G5269C10 0.278348 Biotechnology 1618959.0
Sutro Biopharma Inc. STRO 86936710 0.277729 Biotechnology 1046349.0
Rhythm Pharmaceuticals Inc. RYTM 76243J10 0.272999 Biotechnology 1556115.0
BioAtla Inc. BCAB 09077B10 0.271757 Biotechnology 747410.0
Epizyme Inc. EPZM 29428V10 0.270848 Biotechnology 4475849.0
CytomX Therapeutics Inc. CTMX 23284F10 0.270615 Biotechnology 2972823.0
Avidity Biosciences Inc RNA 05370A10 0.26423 Biotechnology 779012.0
Akero Therapeutics Inc. AKRO 00973Y10 0.254144 Biotechnology 789157.0
Applied Molecular Transport Inc. AMTI 03824M10 0.252447 Biotechnology 876483.0
AnaptysBio Inc. ANAB 03272410 0.244672 Biotechnology 566498.0
Eagle Pharmaceuticals Inc. EGRX 26979610 0.243296 Biotechnology 359059.0
Forma Therapeutics Holdings Inc. FMTX 34633R10 0.234138 Biotechnology 980982.0
Rigel Pharmaceuticals Inc. RIGL 76655960 0.229859 Biotechnology 5548896.0
Nkarta Inc. NKTX 65487U10 0.228413 Biotechnology 958042.0
Stoke Therapeutics Inc. STOK 86150R10 0.224399 Biotechnology 610619.0
AlloVir Inc ALVR 01981810 0.224108 Biotechnology 734075.0
Gossamer Bio Inc. GOSS 38341P10 0.221892 Biotechnology 1383596.0
Y-mAbs Therapeutics Inc. YMAB 98424110 0.216369 Biotechnology 762221.0
Precision BioSciences Inc. DTIL 74019P10 0.211213 Biotechnology 1586838.0
Viking Therapeutics Inc. VKTX 92686J10 0.199955 Biotechnology 2467654.0
Precigen Inc PGEN 74017N10 0.186476 Biotechnology 3293606.0
Chimerix Inc. CMRX 16934W10 0.185073 Biotechnology 2391288.0
Crinetics Pharmaceuticals Inc CRNX 22663K10 0.183497 Biotechnology 516663.0
Chinook Therapeutics Inc KDNY 16961L10 0.180991 Biotechnology 866774.0
Vaxcyte Inc. PCVX 92243G10 0.176411 Biotechnology 527370.0
IDEAYA Biosciences Inc. IDYA 45166A10 0.173139 Biotechnology 591005.0
KalVista Pharmaceuticals Inc. KALV 48349710 0.164857 Biotechnology 725030.0
MiMedx Group Inc. MDXG 60249610 0.157672 Biotechnology 1484352.0
Arcutis Biotherapeutics Inc ARQT 03969K10 0.156559 Biotechnology 567622.0
ZIOPHARM Oncology Inc. ZIOP 98973P10 0.152697 Biotechnology 7537730.0
Deciphera Pharmaceuticals Inc. DCPH 24344T10 0.151923 Biotechnology 1238020.0
Prelude Therapeutics Inc. PRLD 74065P10 0.150966 Biotechnology 693650.0
Geron Corporation GERN 37416310 0.145418 Biotechnology 7319176.0
Cue Biopharma Inc. CUE 22978P10 0.143499 Biotechnology 732796.0
VistaGen Therapeutics Inc. VTGN 92840H20 0.140764 Biotechnology 4632456.0
Selecta Biosciences Inc. SELB 81621210 0.140146 Biotechnology 2916850.0
Anika Therapeutics Inc. ANIK 03525510 0.136901 Biotechnology 275981.0
ORIC Pharmaceuticals Inc ORIC 68622P10 0.125785 Biotechnology 546330.0
Lineage Cell Therapeutics Inc. LCTX 53566P10 0.116237 Biotechnology 3638688.0
Cortexyme Inc. CRTX 22053A10 0.095602 Biotechnology 505293.0
TCR2 Therapeutics Inc. TCRR 87808K10 0.093819 Biotechnology 1019012.0
AVITA Medical Inc. RCEL 05380C10 0.080848 Biotechnology 375963.0
Spero Therapeutics Inc. SPRO 84833T10 0.077454 Biotechnology 352724.0
ACHILLION PHARMACEUTICALS INC COMMON STO 004CVR03 004CVR03 0.00098 Unassigned 51865.0
U.S. Dollar CASH_USD CASH_USD -0.570724 Unassigned -43950240.0